Obesity Drugs, Lean Fatty Liver, and a Sepsis Alert That Misses Kids

A daily briefing on new medical research for clinicians and the curious. Today we cover a phase three trial of the triple hormone agonist retatrutide for obesity, new data on lean fatty liver disease, a sobering look at a widely used pediatric sepsis alert, the global cancer burden from infections, a newly mapped lysosomal stress pathway tied to lymphoma, and a genetic discovery that could open new treatment routes for sickle cell disease.