Early SGLT2 Inhibitors, Menin Inhibitors, and Seasonal Blood Pressure Guidance

Today's briefing covers early SGLT2 inhibitor use in acute heart failure, menin inhibitors transforming treatment for certain genetically defined leukemias, and new seasonal blood pressure guidance from Japan. We also cover a cautionary case of dependence on a potent kratom compound, the newly approved gene therapy for Wiskott-Aldrich syndrome, and what large genetic studies are revealing about osteoarthritis. A quick rundown covers several more studies in genetics, oncology, and aging research.